Radiation & chemotherapy in cancer also can severely damage bone marrow cells. Therefore, stem cells from cancer patients are harvested before radiation or chemotherapy as protection & are re-injected after treatment to restore immune functions. Examination of bone marrow tissue is generally done by biopsy & bone marrow aspiration methods. Bone Marrow Transplants pose severe risks & involve lengthy post-treatments. Bone marrow treatments in India are cost-considerate & at par with the quality of treatment you get in developed countries. Most Indian top surgeons for bone marrow treatment are in fact trained in the west.
Bone Marrow Transplant (BMT) or Cord Blood Transplant is a procedure replacing damaged or destroyed bone marrow cancer cells with healthy bone marrow stem cells. Bone marrow normally is flexible, spongy & well-protected tissue inside bones. Stem cells are a vital component of bone marrow, which primarily are immature cells with capacity to transform into a variety of different cells in our body. These stem cells are also responsible for production of cellular elements like platelets, lymphocytes (WBC) & red blood corpuscles (RBC) within the blood.
Bone marrow cancer is a dreaded medical condition. Before you go for Bone Marrow Transplant there are many things to chalk-out & important decisions to be made. Talk to your doctor about the 4 key elements listed below. He will guide you through these options & recommend what is most appropriate for your medical condition.
- Autologous vs. Allogeneic Transplant
- Cell Source
- Reduced Intensity vs. Standard Intensity Preparative Regimen
(Allogeneic Transplants Only)
- Transplant Timing
India is a specialist destination for Bone Marrow Transplant procedures. Bone Marrow Transplant cost in India are affordable & just a fraction of what you normally pay in the western developed countries. Offering high-tech medical solutions to a large variety of healthcare problems, it is no wonder that India is one of the most favored global health care destinations today.
Travcure provides outstanding Bone Marrow Treatments in the best hospitals for BMT in India. Our 24X7 assistance alongside call & electronic mail services are one of the best you can rely upon. We are associated with the best Bone Marrow Transplant surgeons who are top experts in the country. We ensure you receive transparent, high-quality, seamless, affordable & hassle-free extensive range of BMT treatments to overcome all kinds of medical problems including Leukemia, Sickle Cell Anemia, Neuroblastoma, Multiple Myeloma & other associated genetic diseases.
Autologous Transplantation process involves autografting using patient’s own blood cells. A combination of chemotherapy & drug stimulators like G-CSF is used, in this stem cell treatment to enhance the number of stem cells in marrow & cause them to spill over into blood circulation. Stem cells are subsequently collected from circulating blood through a machine called cell separator. Quite similar to dialysis, this machine collects stem cells & returns rest of the blood into the patient’s circulatory system. These stemcells are thereafter processed, frozen & stored long as the scheduled time of transplant. Eventually cord blood banking costs are a part of treatment plan as this procedure involves stem cell preservation.
Involving allografting, Allogeneic Transplantation procedure replaces destroyed & damaged bone marrow with healthy stem cells from a donor who most often happens to be a brother or sister with same type of tissue. In the absence of a close relative, service of a volunteer donor is sought in this stem cells therapy. The donor will have to undergo human leukocyte antigen (HLA) matching tests to qualify. This is to avoid stem cell rejection eventually resulting in GVHD (Graft-Versus-Host Disease).
Leukemia is a bone marrow cancer resulting in high number abnormal count of white blood cells (WBC). These underdeveloped WBC are called blasts or leukemia cells. Common symptoms of this medical condition include, bruising & bleeding problems, fever, tired feeling alongside increased risk of infections due to lack of normal blood cells. Diagnosing Leukemia is typically done by bone marrow biopsy, or blood tests. However, the exact cause of this cancer is unknown but both environmental & inherited factors are accepted to be involved. Variety of treatments offered for Leukemia include, targeted therapy, radiation, chemotherapy & bone marrow transplant.
Aplastic Anemia is a medical condition which occurs when body stops producing required amount of blood cells. This ailment generates fatigued feeling with uncontrolled bleeding & higher risk of infections. Aplastic Anemia is a rare & serious condition which can develop at any age. It may occur slowly or suddenly & may get worse over a period of time. Aplastic Anemia treatments may include stem cell transplant, blood transfusion or a variety of medications. Aplastic Anemia occurs with damage in bone marrow by shutting production of new blood cells. The illness caused by this condition can be brief or chronic, severe & even fatal in some cases.
Most common in Africans & African-Americans, Sickle Cell Anemia is an inherited blood disorder also found in other racial & ethnic groups among people from India, Caribbean, South & Central America & many other Mediterranean countries. Sickle cell disease causes the normally round & flexible red blood cells in the body to abnormally shape like sickles or like crescent moon. This damaged structure disable the red blood cells smooth travel through small blood vessels thereby often blocking blood flow & triggering loss of necessary oxygen supply to effected tissue. Moreover, sickle red blood cells only live for 10-20 days instead of the normal 120 days lifespan of the normal red blood cells. Alongside anemia & severe pain, this diseased medical condition can also cause permanent damage to heart, brain, lungs, spleen liver & kidneys. It is not a contagious disease but some children are born with sickle cell disease. This generally happens when s/he inherits two sickle hemoglobin genes – one each from mother & father.
Arising out of abnormal immune response of body against tissues & substances, Autoimmune Diseases may restrict or involve certain organs or tissues. Typical treatments for this condition include immunosupression medications which decrease immune response. More than 80 types of illnesses are caused by autoimmunity of which many are chronic, debilitating & life-threatening.
Caused due to malignant plasma cells, Multiple Myeloma affects the bone marrow which is an important part of our immune system. When plasma cells turn cancerous & grow out of control, tumors called plasmacytoma develop in bones. Rarely found in other tissues, more than one plasmacytoma is termed Multiple Myeloma.
Generally caused by one or more abnormalities in genome, most Genetic Diseases are quite rare in nature. Genetic disorders may or may not be congenital, though quite a few may be caused by mutational changes to DNA. More often, the cause & extent of suffering from Genetic Diseases is almost always invariably affected by environmental factors & events relating to personal development of individuals.