What is ABO Incompatible Kidney Transplant?

What is ABO Incompatible Kidney Transplant?

An ABO incompatible kidney transplant is a major surgical procedure that allows some recipients to receive a donor kidney belonging to a different blood group. This is a highly innovative and important technique as it allows a large percentage of kidney recipients to receive kidneys even from donors belonging to a different blood group.

Earlier, a kidney transplant had to be done only after finding a suitable and blood-compatible donor for the recipient. Due to this, a large proportion of the transplant patients did not get compatible kidneys.

Now, this innovative and efficient technique has broken the incompatibility barrier that existed earlier with the surgery’s success rates being as high as a normal kidney transplant.

What is Blood-type Compatibility?

Every person fits into the following four blood-types, and these are at times compatible with some other but not every blood-type, such as:

  • Blood-type A – This blood-type is compatible with blood-type A and O
  • Blood-type B – This blood-type is compatible with blood-type B and O
  • Blood-type AB – This blood-type is compatible with blood-types A, B, AB and O
  • Blood-type O – This blood-type is compatible with blood-type O only (although they can donate universally, these are exclusive blood-type recipients)

In case, a person gets transplanted with a kidney from an incompatible blood-type then the antibodies in the blood (plasma) tends to reject the foreign organ as a result of immune system’s functioning.

Who is a candidate for an ABO Incompatible Kidney Transplant?

A person, who is in overall good health and has no medical history of underlying serious medical conditions, is ideally considered to be a good candidate for an ABO incompatible kidney transplant.

What happens before, during and after the ABO Incompatible Kidney Transplant Surgery?

The doctor will prepare you for the surgery by addressing all your concerns and queries regarding the surgical procedure’s advantages, drawback, benefits and risks as well as the rate of success.

The surgery is a major surgical procedure and the surgeon will administer general anesthesia to avoid pain or discomfort to the patient during the surgery. The ABO incompatibility treatment is performed in multiple sessions from a few weeks prior to the surgery. A process called ‘plasmapheresis’ involves removing plasma from the blood as the plasma is where anti-bodies (immune-system related blood components) are found. These anti-bodies are responsible for detecting and destroying ABO-incompatible organs.

After the anti-bodies are removed from the blood, the surgeon will prepare for the actual kidney transplant procedure. This involves removing the damaged kidney (mostly) and replacing it with the healthy donor kidney. During this procedure the surgeon will be required to inject an intravenous solution of immune globulin which replaces the anti-bodies that are needed to fight infections in the body. This prevents the harmful anti-bodies from returning.

The transplant will be performed only when the anti-bodies in the recipient’s blood have dropped to very low levels.

The plasmapheresis and intravenous immune globulin injections might be needed for a few more sessions after the surgery to ensure that the new (ABO-incompatible) kidney does not get rejected by the body.

After the surgery is completed, the surgeon will likely suggest a few days stay in the hospital to observe for any form of complication or organ rejection symptoms. The doctor might also prescribe certain anti-rejection medicinal drugs to be taken for a few weeks after the surgery. At times, in certain cases of ABO-incompatibility kidney transplant the patient might have to take anti-rejection drugs for a lifetime to prevent outright organ rejection.

What is the success rate of an ABO Incompatible Kidney Transplant surgery?

Due to the steadily developing medical technology there have been major advances in the ABO-incompatible kidney transplant surgery. These advances have meant that the surgery gets more proven and improved significantly.

The success rate for a ABO-incompatibility kidney transplant surgery is very high and most patients are able to see positive long-term benefits of this procedure.

Why choose Travcure for ABO Incompatible Kidney Transplant surgery in India?

Travcure is well-connected to the large network of Indian hospitals and clinics that are spread across all its major cities. These are highly-equipped medical care facilities that have the most advanced and modern instruments and technology at their disposal. The highly-experienced doctors and medical professionals who manage these world-class healthcare facilities ensure that every patient receives the best and most affordable advanced medical and surgical treatment.

Travcure is best known for providing every patient with a truly bespoke treatment package that ensures that the patient gets the most efficient, advanced and affordable ABO-incompatible kidney transplant in India.

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